Correlating RDW, hematocrit, and neutrophil to lymphocyte ratio with patient outcomes in dengue: A retrospective hospital-based study

Dr. Nandhini RV; Dr. L Premkumar; Dr. Jayakumar S

doi:10.22271/23487941.2024.v11.i3a.774

Correlating RDW, hematocrit, and neutrophil to lymphocyte ratio with patient outcomes in dengue: A retrospective hospital-based study

Author(s): Dr. Nandhini RV, Dr. L Premkumar and Dr. Jayakumar S

Abstract: Introduction: Dengue is a major public health problem worldwide, with clinical presentations ranging from mild fever to severe hemorrhagic manifestations. Early detection and monitoring of hematological parameters can play a crucial role in patient management and outcome prediction. This study aimed to explore the correlations between Red Cell Distribution Width (RDW), Hematocrit, and Neutrophil Lymphocyte Ratio (NLR) with the clinical outcomes of dengue to identify potential predictive biomarkers.

Material and Methods: The retrospective analysis was conducted with 150 dengue patients admitted to Saveetha Medical College. Data collected included demographic information, clinical symptoms, laboratory results at admission (RDW, Hematocrit, NLR), and patient outcomes (recovery, complications, mortality). Statistical analyses utilized Pearson’s correlation coefficient to evaluate the relationship between laboratory parameters and clinical outcomes.

Results: The study found significant correlations between the laboratory parameters and patient outcomes. Elevated RDW and Hematocrit were associated with lower recovery rates and higher complication and mortality rates. Similarly, increased NLR correlated negatively with recovery and positively with both complications and mortality. These findings suggest that RDW, Hematocrit, and NLR can serve as important prognostic markers in dengue.

Conclusions: The correlations between these hematological parameters and patient outcomes underscore their potential utility in predicting the severity of dengue. Such insights could help in early risk stratification and targeted management of patients with severe dengue.

DOI: 10.22271/23487941.2024.v11.i3a.774

Pages: 28-31 | 200 Views 87 Downloads

download (572KB)

Vol. 11, Issue 3, Part A (2024)

Correlating RDW, hematocrit, and neutrophil to lymphocyte ratio with patient outcomes in dengue: A retrospective hospital-based study

Related Links